21c Museum Hotel St Louis
1528 Locust street, Saint Louis
Checking price…
Top-rated amenities
Guests rate amenities 9.3/10.
Pool on site
Cool off without leaving.
Guests loved it
Friendly staff
Well reviewed
1,404 guest reviews.
Popular amenities
About 21c Museum Hotel St Louis
Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.
Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.
Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.
Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.
Good to know about 21c Museum Hotel St Louis
Check-in
04:00 PM
Check-out
11:00 AM
Pets
Not allowed
Children
Welcome
How 21c Museum Hotel St Louis's price works
One flat fee
The price is what the hotel charges us plus one small, flat service fee — the same for every guest.
No surveillance pricing
We never use your device, location or browsing history to decide what you pay.
All-in, no surprises
Taxes and known fees are shown up front. What you see is what you book.
21c Museum Hotel St Louis reviews
Very good
1,404 reviews · updated January 2026
Guests loved
- + Friendly staff
- + Unique amenities
- + Comfortable rooms
Worth noting
- – Cleanliness issues
- – Management service shortcomings
- – Parking difficulties
Things to do near 21c Museum Hotel St Louis
1528 Locust street, Saint Louis
Open in Google Maps ↗21c Museum Hotel St Louis property amenities
Internet
- WiFi available
- Free WiFi
Parking & transportation
- Parking
- Valet parking
Pools, spa & fitness
- Fitness facilities
- Fitness center
- Swimming pool
- Hot tub/Jacuzzi
- Massage services
- Spa/wellness center
Food & drink
- Restaurant
- Room service
- Bar
- Shared lounge/TV area
Accessibility
- Facilities for disabled guests
- Wheelchair accessible
Things to do
- Terrace
- Games room
- Billiards
- Board games/puzzles
Services & conveniences
- 24-hour front desk
- Lift / Elevator
- Laundry
- Luggage storage
- Safety deposit box
- Dry cleaning
- Daily housekeeping
- Concierge service
- ATM/cash machine on site
Climate & comfort
- Non-smoking rooms
- Air conditioning
- Heating
- Non-smoking throughout
More
- Business center
- Pets allowed
- Soundproof rooms
- Meeting/banquet facilities
- Private check-in/check-out
- Special diet menus - on request
- Allergy-free room
21c Museum Hotel St Louis room amenities
Bedroom
- Safety deposit box
- Wardrobe or closet
Bathroom
- Shower
- Hair dryer
- Bathrobe
- Toilet
- Private bathroom
- Toilet paper
Food & drink
- Refrigerator
Internet & phone
- Telephone
Comfort
- Air conditioning
- Heating
More
- Desk
- Seating Area
- Alarm clock
- Tile/marble floor
- Bottle of water
- Fireplace
Frequently asked questions about 21c Museum Hotel St Louis
What are the check-in and check-out times at 21c Museum Hotel St Louis?
Check-in starts at 04:00 PM and check-out is by 11:00 AM.
Does 21c Museum Hotel St Louis have WiFi?
WiFi is available at 21c Museum Hotel St Louis. Check your room's details for whether it's free or carries a charge.
Is parking available at 21c Museum Hotel St Louis?
Yes, parking is available at 21c Museum Hotel St Louis, including valet. A fee may apply — see the property's important information.
Does 21c Museum Hotel St Louis have a pool?
Yes — 21c Museum Hotel St Louis has a swimming pool.
Does 21c Museum Hotel St Louis have a spa?
Yes, 21c Museum Hotel St Louis offers spa or wellness facilities.
Is there a gym at 21c Museum Hotel St Louis?
Yes, 21c Museum Hotel St Louis has fitness facilities.
Does 21c Museum Hotel St Louis have a restaurant?
Yes, there is on-site dining at 21c Museum Hotel St Louis. There's also a bar or lounge.
Do the rooms at 21c Museum Hotel St Louis have air conditioning?
Yes, rooms at 21c Museum Hotel St Louis have air conditioning.
Is 21c Museum Hotel St Louis wheelchair accessible?
21c Museum Hotel St Louis offers facilities for guests with disabilities. Contact the property to confirm the specifics for your needs.
Is 21c Museum Hotel St Louis pet-friendly?
No, pets are not allowed at 21c Museum Hotel St Louis.
Is 21c Museum Hotel St Louis family-friendly?
Yes, 21c Museum Hotel St Louis welcomes families.
Is 21c Museum Hotel St Louis non-smoking?
Yes, 21c Museum Hotel St Louis is non-smoking throughout.
How far is 21c Museum Hotel St Louis from Honolulu airport (HNL)?
It's about 4132 mi (straight-line) from Honolulu airport (HNL).
What's the closest beach to 21c Museum Hotel St Louis?
The nearest is Lanikai Beach, about 4119 mi away (straight-line).
What is the cancellation policy at 21c Museum Hotel St Louis?
It depends on the rate you pick — many rooms at 21c Museum Hotel St Louis offer free cancellation. You'll see each room's exact policy before you book.
Are there extra fees at 21c Museum Hotel St Louis?
Any mandatory property fees are shown in your all-in total before you book — no surprises at checkout.
What guest services does 21c Museum Hotel St Louis offer?
21c Museum Hotel St Louis offers services such as concierge, laundry, luggage storage.
Is 21c Museum Hotel St Louis a good place to stay?
Guests rate it 8.8/10 (Very good) across 1,404 reviews.
How does pricing work at 21c Museum Hotel St Louis on travelpluscost?
One honest price: what the hotel charges us plus one small flat fee — the same for everyone, never based on your data. No hidden markup and no fake discounts.
21c Museum Hotel St Louis policies
Groups
When booking more than 7 rooms, different policies and additional supplements may apply.
Children and extra bed policy
Children of any age are allowed. Children up to and including 17 years old stay for free when using an existing bed. You haven't added any cots. You haven't added any extra beds.
Parking
Public parking is possible at a location nearby (reservation is not needed) and charges may be applicable.
You need to know about 21c Museum Hotel St Louis
Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.











